Browsing NIBIO Brage by Author "Clarke, Jihong Liu"
Now showing items 1-16 of 16
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Challenges and prospects of plant-derived oral vaccines against hepatitis b and c viruses
Pantazica, Ana-Maria Madalina; Cucos, Lia-Maria; Stavaru, Crina; Clarke, Jihong Liu; Branza-Nichita, Norica (Peer reviewed; Journal article, 2021-09-28)Hepatitis B and C viruses chronically affect approximately 3.5% of the global population, causing more than 800,000 deaths yearly due to severe liver pathogenesis. Current HBV vaccines have significantly contributed to the ... -
Deep Learning in Hyperspectral Image Reconstruction from Single RGB images—A Case Study on Tomato Quality Parameters
Zhao, Jiangsan; Kechasov, Dmitry; Rewald, Boris; Bodner, Gernot; Verheul, Michel; Clarke, Nicholas; Clarke, Jihong Liu (Peer reviewed; Journal article, 2020-10-07)Hyperspectral imaging has many applications. However, the high device costs and low hyperspectral image resolution are major obstacles limiting its wider application in agriculture and other fields. Hyperspectral image ... -
Degradation of difenoconazole in water and soil: Kinetics, degradation pathways, transformation products identification and ecotoxicity assessment
Man, Yanli; Stenrød, Marianne; Wu, Chi; Almvik, Marit; Holten, Roger; Clarke, Jihong Liu; Yuan, Shankui; Wu, Xiaohu; Xu, Jun; Dong, Fengshou; Zheng, Yongquan; Liu, Xingang (Peer reviewed; Journal article, 2021-06-04)Difenoconazole is a widely used triazole fungicide that has been frequently detected in the environment, but comprehensive study about its environmental fate and toxicity of potential transformation products (TPs) is still ... -
Efficient cellular and humoral immune response and production of virus-neutralizing antibodies by the Hepatitis B Virus S/preS1 16-42 antigen
Pantazica, Ana-Maria; Dobrica, Mihaela-Olivia; Lazar, Catalin; Scurtu, Cristina; Tucureanu, Catalin; Caras, Iuliana; Ionescu, Irina; Costache, Adriana; Onu, Adrian; Clarke, Jihong Liu; Stavaru, Crina; Branza-Nichita, Norica (Peer reviewed; Journal article, 2022-07-22)Despite the availability of improved antiviral therapies, infection with Hepatitis B virus (HBV) remains a3 significant health issue, as a curable treatment is yet to be discovered. Current HBV vaccines relaying on the ... -
Establishment of a piscine myocarditis virus (PMCV) challenge model and testing of a plant-produced subunit vaccine candidate against cardiomyopathy syndrome (CMS) in Atlantic salmon Salmo salar
Su, Hang; van Eerde, André; Steen, Hege; Heldal, Inger; Haugslien, Sissel; Ørpetveit, Irene; Wüstner, Stefanie Caroline; Inami, Makoto; Løvoll, Marie; Rimstad, Espen; Clarke, Jihong Liu (Peer reviewed; Journal article, 2021-08-30)Cardiomyopathy syndrome (CMS) is a severe cardiac disease occurring in the grow-out sea phase of farmed Atlantic salmon with approximately 100 outbreaks annually in Norway. Piscine myocarditis virus (PMCV) is believed to ... -
Grass Carp Reovirus Major Outer Capsid Protein VP4 Interacts with RNA Sensor RIG-I to Suppress Interferon Response
Su, Hang; Fan, Chengjian; Liao, Zhiwei; Yang, Chunrong; Clarke, Jihong Liu; Zhang, Yongan; Su, Jianguo (Peer reviewed; Journal article, 2020-04-06)Diseases caused by viruses threaten the production industry and food safety of aquaculture which is a great animal protein source. Grass carp reovirus (GCRV) has caused tremendous loss, and the molecular function of viral ... -
Hepatitis C virus E2 envelope glycoprotein produced in Nicotiana benthamiana triggers humoral response with virus-neutralizing activity in vaccinated mice
Dobrica, Mihaela-Olivia; van Eerde, André; Tucureanu, Catalin; Onu, Adrian; Paruch, Lisa; Caras, Iuliana; Vlase, Ene; Steen, Hege; Haugslien, Sissel; Alonzi, Dominic; Zitzmann, Nicole; Bock, Ralph; Dubuisson, Jean; Popescu, Costin-Ioan; Stavaru, Crina; Clarke, Jihong Liu; Branza-Nichita, Norica (Peer reviewed; Journal article, 2021-05-18)Chronic infection with hepatitis C virus (HCV) remains a leading cause of liver-related pathologies and a global health problem, currently affecting more than 71 million people worldwide. The development of a prophylactic ... -
Improving the production of AHL lactonase AiiO-AIO6 from Ochrobactrum sp. M231 in intracellular protease-deficient Bacillus subtilis
Xia, Rui; Yang, Yalin; Pan, Xingliang; Gao, Chenchen; Yao, Yuanyuan; Liu, Xuewei; Teame, Tsegay; Zhang, Fengli; Hu, Juan; Ran, Chao; Zhang, Zhen; Clarke, Jihong Liu; Zhou, Zhigang (Peer reviewed; Journal article, 2020-08-05)Quorum quenching (QQ) blocks bacterial cell-to-cell communication (i.e., quorum sensing), and is a promising antipathogenic strategy to control bacterial infection via inhibition of virulence factor expression and biofilm ... -
In-depth characterization of Trichoderma reesei cellobiohydrolase TrCel7A produced in Nicotiana benthamiana reveals limitations of cellulase production in plants by host-specific post-translational modifications
van Eerde, André; Varnai, Aniko; Jameson, John-Kristian; Paruch, Lisa; Moen, Anders; Anonsen, Jan Haug; Chylenski, Piotr; Steen, Hege; Heldal, Inger; Bock, Ralph; Eijsink, Vincent; Clarke, Jihong Liu (Journal article; Peer reviewed, 2019)Sustainable production of biofuels from lignocellulose feedstocks depends on cheap enzymes for degradation of such biomass. Plants offer a safe and cost‐effective production platform for biopharmaceuticals, vaccines and ... -
Plant-produced Vaccines: Future Applications in Aquaculture
Su, Hang; Yakovlev, Igor; Eerde, André van; Su, Jianguo; Clarke, Jihong Liu (Peer reviewed; Journal article, 2021-08-12)Aquaculture has undergone rapid development in the past decades. It provides a large part of high-quality protein food for humans, and thus, a sustainable aquaculture industry is of great importance for the worldwide food ... -
Pollution by Antibiotics and Antimicrobial Resistance in LiveStock and Poultry Manure in China, and Countermeasures
Tian, Ming; He, Xinmiao; Feng, Yanzhong; Wang, Wentao; Chen, Heshu; Gong, Ming; Liu, Di; Clarke, Jihong Liu; van Eerde, André (Peer reviewed; Journal article, 2021-05-06)The demand for animal protein has increased considerably worldwide, especially in China, where large numbers of livestock and poultry are produced. Antibiotics have been widely applied to promote growth and prevent diseases. ... -
Production of tetravalent dengue virus envelope protein domain III based antigens in lettuce chloroplasts and immunologic analysis for future oral vaccine development
van Eerde, André; Gottschamel, Johanna; Bock, Ralph; Hansen, Kristine Eraker Aasland; Munangandu, Hetron Mweemba; Daniell, Henry; Clarke, Jihong Liu (Journal article; Peer reviewed, 2018-12-22)Dengue fever is a mosquito (Aedes aegypti) ‐transmitted viral disease that is endemic in more than 125 countries around the world. There are four serotypes of the dengue virus (DENV 1‐4) and a safe and effective dengue ... -
Propionate induces intestinal oxidative stress via Sod2 propionylation in zebrafish
Ding, Qianwen; Zhang, Zhen; Li, Yu; Liu, Hongliang; Hao, Qiang; Yang, Yalin; Ringø, Einar; Olsen, Rolf Erik; Clarke, Jihong Liu; Ran, Chao; Zhou, Zhigang (Peer reviewed; Journal article, 2021-06-25)Propionate and propionyl-CoA accumulation have been associated with the development of mitochondrial dysfunction. In this study, we show that propionate induces intestinal damage in zebrafish when fed a high-fat diet (HFD). ... -
Successful Production and Ligninolytic Activity of a Bacterial Laccase, Lac51, Made in Nicotiana benthamiana via Transient Expression
van Eerde, André; Varnai, Aniko; Wang, Yanliang; Paruch, Lisa; Jameson, John-Kristian; Qiao, Fen; Eiken, Hans Geir; Su, Hang; Eijsink, Vincent; Clarke, Jihong Liu (Peer reviewed; Journal article, 2022-05-13)Giant panda could have bamboo as their exclusive diet for about 2 million years because of the contribution of numerous enzymes produced by their gut bacteria, for instance laccases. Laccases are blue multi-copper oxidases ... -
Transcriptional profiling of wheat (Triticum aestivum L.) during a compatible interaction with the cereal cyst nematode Heterodera avenae
Qiao, Fen; Kong, Ling-An; Peng, Huan; Huang, Wen-Kun; Wu, Du-Qing; Liu, Shi-Ming; Clarke, Jihong Liu; Qiu, De-Wen; Peng, De-Liang (Journal article; Peer reviewed, 2019-02-18)Cereal cyst nematode (CCN, Heterodera avenae) presents severe challenges to wheat (Triticum aestivum L.) production worldwide. An investigation of the interaction between wheat and CCN can greatly improve our understanding ... -
Transcriptome profiling and in silico detection of the antimicrobial peptides of red king crab Paralithodes camtschaticus
Yakovlev, Igor; Lysøe, Erik; Heldal, Inger; Steen, Hege; Hagen, Snorre; Clarke, Jihong Liu (Peer reviewed; Journal article, 2020-07-29)Endogenous antimicrobial peptides (AMPs) are evolutionarily ancient factors of innate immunity, which are produced by all multicellular organisms and play a key role in their protection against infection. Red king crab ...