• Base-Editing-Mediated Artificial Evolution of OsALS1 In Planta to Develop Novel Herbicide-Tolerant Rice Germplasms 

      Kuang, Yongjie; Li, Shaofang; Ren, Bin; Yan, Fang; Spetz, Carl; Li, Xiangju; Zhou, Xueping; Zhou, Huanbin (Peer reviewed; Journal article, 2020-04-06)
      Recently developed CRISPR-mediated base editors, which enable the generation of numerous nucleotide changes in target genomic regions, have been widely adopted for gene correction and generation of crop germplasms containing ...
    • A New Era in Herbicide-Tolerant Crops Development by Targeted Genome Editing 

      Gosavi, Gokul; Ren, Bin; Li, Xiangjiu; Zhou, Xueping; Spetz, Carl; Zhou, Huanbin (Peer reviewed; Journal article, 2022)
      Weeds are one of the biggest problems that modern agriculture is facing worldwide due to the impact they have on crop productivity. Thus, there is a necessity to develop crop varieties with herbicide resistance or tolerance, ...
    • SpRY greatly expands the genome editing scope in rice with highly flexible PAM recognition 

      Xu, Ziyan; Kuang, Yongjie; Ren, Bin; Yan, Daqi; Yan, Fang; Spetz, Carl; Sun, Wenxian; Wang, Guirong; Zhou, Xueping; Zhou, Huanbin (Peer reviewed; Journal article, 2021-01-04)
      Background Plant genome engineering mediated by various CRISPR-based tools requires specific protospacer adjacent motifs (PAMs), such as the well-performed NGG, NG, and NNG, to initiate target recognition, which notably ...